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Symbol Name ID |
Cx3cr1
C-X3-C motif chemokine receptor 1 MGI:1333815 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Asthma |
| Disease(s) Associated with CX3CR1 | |
| asthma |
| Mouse Phenotypes | immune system phenotype |
impaired macrophage chemotaxis |
increased dendritic cell number |
decreased NK cell number |
decreased monocyte cell number |
abnormal microglial cell morphology |
microgliosis |
abnormal leukocyte physiology |
abnormal NK cell physiology |
abnormal microglial cell physiology |
abnormal splenocyte physiology |
abnormal dendritic cell physiology |
increased susceptibility to experimental autoimmune encephalomyelitis |
decreased inflammatory response |
brain inflammation |
increased susceptibility to bacterial infection induced morbidity/mortality |
abnormal response to transplant |
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| Availability | Mouse Genotype | |||||||||||||||||
| Cx3cr1tm1Ifc/Cx3cr1tm1Ifc | * | |||||||||||||||||
| Cx3cr1tm1Litt/Cx3cr1tm1Litt | * | |||||||||||||||||
| Cx3cr1tm1Zm/Cx3cr1tm1Zm | ||||||||||||||||||
| Cx3cr1tm1Litt/Cx3cr1+ | ||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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